Sophia C Kamran, MD

Sophia C. Kamran, MD, is a Radiation Oncologist at Mass General Brigham/Massachusetts General Hospital and an Associate Professor of Radiation Oncology at Harvard Medical School. She is an Associate Member of the Broad Institute of MIT and Harvard. In her clinic, Dr. Kamran specializes in the treatment of genitourinary cancers. Her research interests focus on the application of computational genomic approaches to characterize tumor evolution to treatment and understand mechanisms of toxicity and resistance to radiation and chemoradiation. Her goal is to use these approaches to guide the design of clinical trials of high-precision radiation therapy to enable personalized approaches to delivery of radiation therapy for patients with genitourinary cancers. Dr. Kamran is actively involved with multiple professional organizations including the American Urological Association, NRG Oncology, the American Board of Radiology (ABR), the American Society for Radiation Oncology (ASTRO), the Radiation Research Society, the American Society for Clinical Oncology (ASCO), and the Massachusetts Prostate Cancer Coalition. She was the 2023 Co-Chair of the Renal & Rare Tumors Track for the ASCO Genitourinary Cancers Symposium and the Organizing Chair for the 2023 Coffey-Holden Prostate Cancer Academy Meeting, sponsored by the Prostate Cancer Foundation. She serves on the Editorial Board for Clinical Genitourinary Cancer and is a GU Associate Section Editor for Practical Radiation Oncology. Dr. Kamran is a part of the NRG Oncology Genitourinary Cancer Committee and was selected as a 2023 NRG Health Care Access Fellow. She currently serves on ASCO’s Annual Meeting Planning Committee for the GU track.  Her work has been published in many high-quality journals, including The New England Journal of Medicine, Clinical Cancer Research, JAMA Oncology, European Urology, and others. 

Dr. Kamran holds a bachelor’s degree in Biological Engineering from the Massachusetts Institute of Technology, which she attended as a Gates Millennium Scholar. She received her medical degree cum laude from Harvard Medical School. During her medical training, she completed a Howard Hughes Medical Student Research Fellowship. She completed a transitional year internship at Memorial Sloan Kettering Cancer Center and residency training at the Harvard Radiation Oncology Program.