Highlights
Age Groups Seen
- Adults
- Geriatrics
Languages
- Italian
- English
Gender
FemaleAbout Sabrina Paganoni
Dr. Paganoni is an Associate Professor at Harvard Medical School and works as a physician scientist at the Healey Center for ALS at Massachusetts General Hospital and at Spaulding Rehabilitation Hospital.Her research focuses on clinical trials and therapy development for ALS.
She has served as PI of several ALS clinical trials and has been using novel trial designs, novel endpoints and digital technology tools to innovate the way investigational products are tested in ALS. She is the co-PI of the HEALEY ALS Platform Trial, the first platform trial for ALS in the world. She recently reported the positive results of the CENTAUR trial and is the co-Chair of the global PHOENIX trial. She is also working with people with Primary Lateral Sclerosis (PLS), a rare form of Motor Neuron Disease, and Hereditary Spastic Paraplegia (HSP).
She co-chairs the PLS Task Force and the PLS registry of the Northeast ALS Consortium (NEALS). She is working with other Harvard researchers on developing new assistive technology devices that can improve function and quality of life for people with ALS and other forms of Motor Neuron Disease. Dr. Paganoni published >100 peer-reviewed papers. She is an editorial board member for Muscle and Nerve and the American Journal of PM&R where she is also Associate Editor for the Section Evidence-Based Physiatry/Cochrane Corner.
Her research has been funded by the NIH, foundations, and industry. She received several awards for her work including the NIH Rehabilitation Medicine Scientist Training Program Award (2012), the American Academy of Neurology / ALS Association Three-Year Career Development Award in ALS (2017), the American Association of Neuromuscular & Electrodiagnostic Medicine Scientific Impact Award (2019), the Top 10 Clinical Research Achievement Award (2021), and the Martin Prize for Excellence in Clinical Research Award (2021).Dr. Paganoni holds 3 Board Certifications (Physical Medicine and Rehabilitation, Neuromuscular Medicine, and Electrodiagnostic Medicine). She is a member of the Association of Academic Physiatrists (AAP), American Academy of Neurology (AAN), and American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM).
Locations
- Massachusetts General Neurology Clinic
- 55 Fruit Street, Wang Building, 8th Floor, Suite 835, Boston, MA 02114
- Get Directions
- phone: 617-724-3914
- fax: 617-724-7290
Expertise
Education
- Fellowship: Brigham and Women's Hospital, Neuromuscular Disease, 2013
- Fellowship: Mass General Brigham Combined Training Program, Neuromuscular Medicine, 2012
- Residency: Spaulding Rehabilitation Hospital, Physical Medicine & Rehab, 2011
- Internship: Weiss Memorial Hospital, Internal Medicine, 2008
- Medical Education: Northwestern University, Neuroscience, 2005
- Internship: University of Milan, 2000
- Medical Education: University of Milan-Medical School, 1999
Board Certifications
- Physical Medicine and Rehabilitation: American Board of Physical Medicine and Rehabilitation, 2012
- Neuromuscular Medicine: American Board of Physical Medicine and Rehabilitation, 2012
Insurance
- Aetna
- Beech Street
- Blue Cross Blue Shield
- Blue Cross Blue Shield - Indemnity
- Blue Cross Blue Shield Medicare
- Cigna
- Commonwealth Care Alliance
- Coventry
- Fallon Health
- Harvard Pilgrim Health Care
- Humana
- Maine Community Health Options
- Mass General Brigham Health Plan
- MassHealth
- Medicaid ME
- Medicaid NH
- Medicaid RI
- Medicaid VT
- Medicare
- Medicare ACO
- Multiplan
- Railroad Medicare
- Senior Whole Health
- TriCare
- Tufts Health Plan
- Tufts Medicare Preferred
- United Health Care
- Wellpoint
- WellSense
- WellSense NH
Ratings & Reviews
4.9 out of 5
53 ratings, 25 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- Reviewed on 2/8/2026
Extremely professional, understanding and caring experience.
- Reviewed on 2/1/2026
I genuinely appreciated the time you took to listen to me and provide follow-up care. This goes a long way when dealing with health issues, knowing that you were truly understood.
- Reviewed on 1/12/2026
This was my first visit. I was treated with care and respect.
- Reviewed on 1/12/2026
The care provider was extremely supportive and professional.
- Reviewed on 12/14/2025
Very knowledgeable and professional about ALS. As a first time patient with ALS it can be very challenging to understand everything about what the total picture is. The team made it easy to understand and provide a better understanding leading to hope that there are many ways to improve the situation.
- Reviewed on 12/11/2025
I thought she was wonderful. She was kind and caring and respectful and I feel very fortunate that I have that doctor to be on my team and to take care of me.
- Reviewed on 12/11/2025
She was always very easy to talk to, very kind, you could relate to her, and very informative. She'd listen to our questions, we could ask any type of questions, and then she'd give her feedback and tell us what she thought. She was absolutely amazing. Thank you.
- Reviewed on 11/20/2025
She's the best.
- Reviewed on 11/10/2025
she took the time to explain things clearly. she listened well and answered all my questions. she knows her area of expertise perfectly.
- Reviewed on 10/19/2025
Difícil writing
- Reviewed on 9/29/2025
Everyone at Massachusetts General Hospital was Excellent!
- Reviewed on 9/14/2025
Dr Paganoni is an exceptional Dr and person.
- Reviewed on 9/7/2025
This was the best health care experience I have ever had.
- Reviewed on 9/7/2025
Excellent, very understanding
- Reviewed on 8/10/2025
Very professional experience.
- Reviewed on 7/20/2025
She was very thorough in her examination of me, listened to my history and asked questions. Although she did not have all notes from referring doctors, she assured me that she would seek them out to fully evaluate my case in preparation for follow up visit.
- Reviewed on 7/9/2025
She gave me confidence that she is knowledgeable and experienced in this field, something very important to me
- Reviewed on 6/30/2025
Overall very pleased with my visit and the discussed plan of care going forward. Dr. Paganoni was very thorough, knowledgeable and compassionate. I feel I am in the best hands for continued treatment.
- Reviewed on 6/15/2025
Excellent presentation and listening skills. Extremely knowledgeable about my condition and most helpful working out further diagnostic tests and possible future treatments.
- Reviewed on 6/14/2025
Please find a cure for ALS as soon as possible :)
- Reviewed on 6/9/2025
The dr was extremely attentive, caring , knowledgeable and very professional. I have taken the patient to many appointments over the past 10 years and this was the most thorough. A true professional experience.
- Reviewed on 5/21/2025
I've been working with Dr. Paganoni for probably the last year, the better part of the last year. My case has been quite a difficult one to diagnose. I think she's been very clear, very forthright, and very helpful in the whole process. I couldn't ask for more. And her whole group has just been extremely helpful in terms of follow-up. So I would give her top marks, and I'm very pleased. I just wish I were better.
- Reviewed on 5/11/2025
This was my first visit and it was a very thorough one, managed with care and compassion.
- Reviewed on 5/2/2025
Dr. Paganoni was kind, knowledgeable, beyond belief. She was super thorough. I couldn't say anything other than blew my standards away. And I'm very grateful that I got to meet with her.
- Reviewed on 5/2/2025
I've always had the most admiration for this team, given the difficult situation. I always enjoy them and can't imagine any place would be any better. Thank you.